New cover art for Jessica’s Journal review for Cell Press: Trends in Biotechnology. #dna #rna #biotechnology #generegulation @nanobioart #transcription #nanomaterials On The Cover: Nucleic acid nanostructures have gained significant moment in the field of gene regulation. Such nanomaterials are now being designed with an emphasis on endosomal escape to maximize their gene silencing capabilities. Much like a biometric marker, these nanostructures enable nucleic acids to pass through the outer cell membrane. In pages 983–994 of this issue, Gudipati and colleagues discuss the design principles surrounding this new class of materials, their potential for enhanced gene regulation, and the challenges they face for future clinical advancement. Cover image conceptualized by Jessica Rouge and Joseph Luciani and graphics designed by Joseph Luciani

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